Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery

Cellular homeostasis relies on both the chaperoning of proteins and the intracellular degradation system that delivers cytoplasmic constituents to the lysosome, a process known as autophagy. The crosstalk between these processes and their underlying regulatory mechanisms is poorly understood. Here,...

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Detalles Bibliográficos
Autores principales: Backe, Sarah J., Sager, Rebecca A., Heritz, Jennifer A., Wengert, Laura A., Meluni, Katherine A., Aran-Guiu, Xavier, Panaretou, Barry, Woodford, Mark R., Prodromou, Chrisostomos, Bourboulia, Dimitra, Mollapour, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529509/
https://www.ncbi.nlm.nih.gov/pubmed/37453059
http://dx.doi.org/10.1016/j.celrep.2023.112807

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