Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells

Nutrient starvation drives yeast meiosis, whereas retinoic acid (RA) is required for mammalian meiosis through its germline target Stra8. Here, by using single-cell transcriptomic analysis of wild-type and Stra8-deficient juvenile mouse germ cells, our data show that the expression of nutrient trans...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyu, Liu, Yan, Sosa, Froylan, Gunewardena, Sumedha, Crawford, Peter A., Zielen, Amanda C., Orwig, Kyle E., Wang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529640/
https://www.ncbi.nlm.nih.gov/pubmed/37405912
http://dx.doi.org/10.1016/j.celrep.2023.112749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529640/
https://www.ncbi.nlm.nih.gov/pubmed/37405912
http://dx.doi.org/10.1016/j.celrep.2023.112749

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