Cargando…
Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells
Nutrient starvation drives yeast meiosis, whereas retinoic acid (RA) is required for mammalian meiosis through its germline target Stra8. Here, by using single-cell transcriptomic analysis of wild-type and Stra8-deficient juvenile mouse germ cells, our data show that the expression of nutrient trans...
Autores principales: | Zhang, Xiaoyu, Liu, Yan, Sosa, Froylan, Gunewardena, Sumedha, Crawford, Peter A., Zielen, Amanda C., Orwig, Kyle E., Wang, Ning |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529640/ https://www.ncbi.nlm.nih.gov/pubmed/37405912 http://dx.doi.org/10.1016/j.celrep.2023.112749 |
Ejemplares similares
-
Nutrient restriction synergizes with retinoic acid to induce mammalian meiotic initiation in vitro
por: Zhang, Xiaoyu, et al.
Publicado: (2021) -
Chemical reprogramming of Caenorhabditis elegans germ cell fate
por: Morgan, Clinton T., et al.
Publicado: (2009) -
Germline stem cells are critical for sexual fate decision of germ cells
por: Tanaka, Minoru
Publicado: (2016) -
Deciphering the decisive factors driving fate bifurcations in somatic cell reprogramming
por: Long, Chunshen, et al.
Publicado: (2023) -
PRAME as diagnostic marker and as regulator for cell fate decisions in germ cell cancers
por: Neuhaus, Nina
Publicado: (2016)