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FUT8-Mediated Core Fucosylation Promotes the Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease with unclear underlying molecular mechanisms and limited therapeutic options. This study aimed to explore the role of core fucosylation and the only glycosyltransferase FUT8 in PAH. We observed increased core fucosylation...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Lin, Wenchao, Zeng, Xiaofang, Zhang, Mengqiu, Chen, Qin, Tang, Yiyang, Sun, Jing, Liang, Benhui, Zha, Lihuang, Yu, Zaixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529761/
https://www.ncbi.nlm.nih.gov/pubmed/37196106
http://dx.doi.org/10.14336/AD.2023.0218