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In Silico Evaluation of the Potential Association of the Pathogenic Mutations of Alpha Synuclein Protein with Induction of Synucleinopathies

Alpha synuclein (α-Syn) is a neuronal protein encoded by the SNCA gene and is involved in the development of Parkinson’s disease (PD). The objective of this study was to examine in silico the functional implications of non-synonymous single nucleotide polymorphisms (nsSNPs) in the SNCA gene. We used...

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Detalles Bibliográficos
Autores principales: Elnageeb, Mohamed E., Elfaki, Imadeldin, Adam, Khalid M., Ahmed, Elsadig Mohamed, Elkhalifa, Elkhalifa M., Abuagla, Hytham A., Ahmed, Abubakr Ali Elamin Mohamed, Ali, Elshazali Widaa, Eltieb, Elmoiz Idris, Edris, Ali M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529770/
https://www.ncbi.nlm.nih.gov/pubmed/37754311
http://dx.doi.org/10.3390/diseases11030115