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Real-World Evidence on the Prevalence of Molar Incisor Hypomineralization in School Children from Bucharest, Romania

Molar incisor hypomineralization (MIH) is an understudied and underrecognized clinical entity occurring in children. We performed a cross-sectional study to determine the real-world prevalence of MIH among school children undergoing routine dental checkups at one primary and middle school in Buchare...

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Autores principales: Ciocan, Beatrice, Săndulescu, Mihai, Luca, Rodica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529811/
https://www.ncbi.nlm.nih.gov/pubmed/37761524
http://dx.doi.org/10.3390/children10091563
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author Ciocan, Beatrice
Săndulescu, Mihai
Luca, Rodica
author_facet Ciocan, Beatrice
Săndulescu, Mihai
Luca, Rodica
author_sort Ciocan, Beatrice
collection PubMed
description Molar incisor hypomineralization (MIH) is an understudied and underrecognized clinical entity occurring in children. We performed a cross-sectional study to determine the real-world prevalence of MIH among school children undergoing routine dental checkups at one primary and middle school in Bucharest, Romania. Our study cohort consisted of 266 children with evaluable data, of which 143 (53.8%) were males, with a median age of 10 years old (interquartile range: 8–11 years). In this study cohort, we have identified a prevalence of 14.3% (n = 38 cases) of MIH. Among patients diagnosed with MIH, hypomineralizations were present in 47.4% of children on the maxillary first molar, 92.1% on the mandibular first molar, 94.7% on the maxillary incisor, 36.8% on the mandibular incisor, and 5.3% on the deciduous second molar. We identified the maxillary incisor and the mandibular first molar as the most important examined sites significantly associated with the presence of MIH (p < 0.0001 each), highlighting the importance of paying focused attention to these sites during routine dental care in children. In order to establish the diagnosis of MIH, findings of hypomineralization should be present on at least one permanent first molar, according to the case definition currently in use; this definition does not include findings on the incisors. Thus, our finding that hypomineralization of the maxillary incisors is significantly associated with MIH is particularly important. While incisor hypomineralization is not diagnostic of MIH, based on our results, we conclude that it should raise the suspicion of MIH and lead to an attentive examination of the permanent molars in order to establish timely diagnosis.
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spelling pubmed-105298112023-09-28 Real-World Evidence on the Prevalence of Molar Incisor Hypomineralization in School Children from Bucharest, Romania Ciocan, Beatrice Săndulescu, Mihai Luca, Rodica Children (Basel) Article Molar incisor hypomineralization (MIH) is an understudied and underrecognized clinical entity occurring in children. We performed a cross-sectional study to determine the real-world prevalence of MIH among school children undergoing routine dental checkups at one primary and middle school in Bucharest, Romania. Our study cohort consisted of 266 children with evaluable data, of which 143 (53.8%) were males, with a median age of 10 years old (interquartile range: 8–11 years). In this study cohort, we have identified a prevalence of 14.3% (n = 38 cases) of MIH. Among patients diagnosed with MIH, hypomineralizations were present in 47.4% of children on the maxillary first molar, 92.1% on the mandibular first molar, 94.7% on the maxillary incisor, 36.8% on the mandibular incisor, and 5.3% on the deciduous second molar. We identified the maxillary incisor and the mandibular first molar as the most important examined sites significantly associated with the presence of MIH (p < 0.0001 each), highlighting the importance of paying focused attention to these sites during routine dental care in children. In order to establish the diagnosis of MIH, findings of hypomineralization should be present on at least one permanent first molar, according to the case definition currently in use; this definition does not include findings on the incisors. Thus, our finding that hypomineralization of the maxillary incisors is significantly associated with MIH is particularly important. While incisor hypomineralization is not diagnostic of MIH, based on our results, we conclude that it should raise the suspicion of MIH and lead to an attentive examination of the permanent molars in order to establish timely diagnosis. MDPI 2023-09-16 /pmc/articles/PMC10529811/ /pubmed/37761524 http://dx.doi.org/10.3390/children10091563 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ciocan, Beatrice
Săndulescu, Mihai
Luca, Rodica
Real-World Evidence on the Prevalence of Molar Incisor Hypomineralization in School Children from Bucharest, Romania
title Real-World Evidence on the Prevalence of Molar Incisor Hypomineralization in School Children from Bucharest, Romania
title_full Real-World Evidence on the Prevalence of Molar Incisor Hypomineralization in School Children from Bucharest, Romania
title_fullStr Real-World Evidence on the Prevalence of Molar Incisor Hypomineralization in School Children from Bucharest, Romania
title_full_unstemmed Real-World Evidence on the Prevalence of Molar Incisor Hypomineralization in School Children from Bucharest, Romania
title_short Real-World Evidence on the Prevalence of Molar Incisor Hypomineralization in School Children from Bucharest, Romania
title_sort real-world evidence on the prevalence of molar incisor hypomineralization in school children from bucharest, romania
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529811/
https://www.ncbi.nlm.nih.gov/pubmed/37761524
http://dx.doi.org/10.3390/children10091563
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