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Cell state transition analysis identifies interventions that improve control of Mycobacterium tuberculosis infection by susceptible macrophages

Understanding cell state transitions and purposefully controlling them to improve therapies is a longstanding challenge in biological research and medicine. Here, we identify a transcriptional signature that distinguishes activated macrophages from the tuberculosis (TB) susceptible and resistant mic...

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Detalles Bibliográficos
Autores principales: Yabaji, Shivraj M., Rukhlenko, Oleksii S., Chatterjee, Sujoy, Bhattacharya, Bidisha, Wood, Emily, Kasaikina, Marina, Kholodenko, Boris N., Gimelbrant, Alexander A., Kramnik, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530096/
https://www.ncbi.nlm.nih.gov/pubmed/37756395
http://dx.doi.org/10.1126/sciadv.adh4119