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“Click and mortar” opportunities for digitization and consumerism in trials

BACKGROUND: Digitization (using novel digital tools and strategies) and consumerism (taking a consumer-oriented approach) are increasingly commonplace in clinical trials, but the implications of these changes are not well described. METHODS: We assembled a group of trial experts from academia, indus...

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Autores principales: Randell, Rachel L., Hornik, Christoph P., Curtis, Lesley, Hernandez, Adrian F., Denwood, Tom, Nebeker, Camille, Sugarman, Jeremy, Tyl, Benoit, Murakami, Masahiro, Wilberforce, Leslie Oley, Pagoto, Sherry, Vedin, Ola, Andersson, Tomas, Carrasquillo, Olveen, Dolor, Rowena, Kollins, Scott H., Pellegrino, Jill, Ranney, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530120/
https://www.ncbi.nlm.nih.gov/pubmed/37481202
http://dx.doi.org/10.1016/j.cct.2023.107304
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author Randell, Rachel L.
Hornik, Christoph P.
Curtis, Lesley
Hernandez, Adrian F.
Denwood, Tom
Nebeker, Camille
Sugarman, Jeremy
Tyl, Benoit
Murakami, Masahiro
Wilberforce, Leslie Oley
Pagoto, Sherry
Vedin, Ola
Andersson, Tomas
Carrasquillo, Olveen
Dolor, Rowena
Kollins, Scott H.
Pellegrino, Jill
Ranney, Megan L.
author_facet Randell, Rachel L.
Hornik, Christoph P.
Curtis, Lesley
Hernandez, Adrian F.
Denwood, Tom
Nebeker, Camille
Sugarman, Jeremy
Tyl, Benoit
Murakami, Masahiro
Wilberforce, Leslie Oley
Pagoto, Sherry
Vedin, Ola
Andersson, Tomas
Carrasquillo, Olveen
Dolor, Rowena
Kollins, Scott H.
Pellegrino, Jill
Ranney, Megan L.
author_sort Randell, Rachel L.
collection PubMed
description BACKGROUND: Digitization (using novel digital tools and strategies) and consumerism (taking a consumer-oriented approach) are increasingly commonplace in clinical trials, but the implications of these changes are not well described. METHODS: We assembled a group of trial experts from academia, industry, non-profit, and government to discuss implications of this changing trial landscape and provide guidance. RESULTS: Digitization and consumerism can increase the volume and diversity of trial participants and expedite recruitment. However, downstream bottlenecks, challenges with retention, and serious issues with equity, ethics, and security can result. A “click and mortar” approach, combining approaches from novel and traditional trials with the thoughtful use of technology, may optimally balance opportunities and challenges facing many trials. CONCLUSION: We offer expert guidance and three “click and mortar” approaches to digital, consumer-oriented trials. More guidance and research are needed to navigate the associated opportunities and challenges.
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spelling pubmed-105301202023-09-27 “Click and mortar” opportunities for digitization and consumerism in trials Randell, Rachel L. Hornik, Christoph P. Curtis, Lesley Hernandez, Adrian F. Denwood, Tom Nebeker, Camille Sugarman, Jeremy Tyl, Benoit Murakami, Masahiro Wilberforce, Leslie Oley Pagoto, Sherry Vedin, Ola Andersson, Tomas Carrasquillo, Olveen Dolor, Rowena Kollins, Scott H. Pellegrino, Jill Ranney, Megan L. Contemp Clin Trials Article BACKGROUND: Digitization (using novel digital tools and strategies) and consumerism (taking a consumer-oriented approach) are increasingly commonplace in clinical trials, but the implications of these changes are not well described. METHODS: We assembled a group of trial experts from academia, industry, non-profit, and government to discuss implications of this changing trial landscape and provide guidance. RESULTS: Digitization and consumerism can increase the volume and diversity of trial participants and expedite recruitment. However, downstream bottlenecks, challenges with retention, and serious issues with equity, ethics, and security can result. A “click and mortar” approach, combining approaches from novel and traditional trials with the thoughtful use of technology, may optimally balance opportunities and challenges facing many trials. CONCLUSION: We offer expert guidance and three “click and mortar” approaches to digital, consumer-oriented trials. More guidance and research are needed to navigate the associated opportunities and challenges. 2023-09 2023-07-20 /pmc/articles/PMC10530120/ /pubmed/37481202 http://dx.doi.org/10.1016/j.cct.2023.107304 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ).
spellingShingle Article
Randell, Rachel L.
Hornik, Christoph P.
Curtis, Lesley
Hernandez, Adrian F.
Denwood, Tom
Nebeker, Camille
Sugarman, Jeremy
Tyl, Benoit
Murakami, Masahiro
Wilberforce, Leslie Oley
Pagoto, Sherry
Vedin, Ola
Andersson, Tomas
Carrasquillo, Olveen
Dolor, Rowena
Kollins, Scott H.
Pellegrino, Jill
Ranney, Megan L.
“Click and mortar” opportunities for digitization and consumerism in trials
title “Click and mortar” opportunities for digitization and consumerism in trials
title_full “Click and mortar” opportunities for digitization and consumerism in trials
title_fullStr “Click and mortar” opportunities for digitization and consumerism in trials
title_full_unstemmed “Click and mortar” opportunities for digitization and consumerism in trials
title_short “Click and mortar” opportunities for digitization and consumerism in trials
title_sort “click and mortar” opportunities for digitization and consumerism in trials
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530120/
https://www.ncbi.nlm.nih.gov/pubmed/37481202
http://dx.doi.org/10.1016/j.cct.2023.107304
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