Divergent total syntheses of ITHQ-type bis-β-carboline alkaloids by regio-selective formal aza-[4 + 2] cycloaddition and late-stage C–H functionalization

We herein report the first total syntheses of several bis-β-carboline alkaloids, picrasidines G, S, R, and T, and natural product-like derivatives in a divergent manner. Picrasidines G, S, and T feature an indolotetrahydroquinolizinium (ITHQ) skeleton, while picrasidine R possesses a 1,4-diketone li...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qixuan, Guo, Fusheng, Wang, Jin, Lei, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530148/
https://www.ncbi.nlm.nih.gov/pubmed/37772099
http://dx.doi.org/10.1039/d3sc03722c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530148/
https://www.ncbi.nlm.nih.gov/pubmed/37772099
http://dx.doi.org/10.1039/d3sc03722c

Ejemplares similares