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Polysome propensity and tunable thresholds in coding sequence length enable differential mRNA stability
The half-life of mRNAs, as well as their translation, increases in proportion to the optimal codons, indicating a tight coupling of codon-dependent differential translation and degradation. Little is known about the regulation of this coupling. We found that the mRNA stability gain in yeast depends...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530222/ https://www.ncbi.nlm.nih.gov/pubmed/37756413 http://dx.doi.org/10.1126/sciadv.adh9545 |