Differential Effects of the Betablockers Carvedilol, Metoprolol and Bisoprolol on Cardiac K(v)4.3 (I(to)) Channel Isoforms

Cardiac K(v)4.3 channels contribute to the transient outward K(+) current, I(to), during early repolarization of the cardiac action potential. Two different isoforms of K(v)4.3 are present in the human ventricle and exhibit differential remodeling in heart failure (HF). Cardioselective betablockers...

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Detalles Bibliográficos
Autores principales: Rahm, Ann-Kathrin, Hackbarth, Juline, Müller, Mara E., Pfeiffer, Julia, Gampp, Heike, Petersenn, Finn, Rivinius, Rasmus, Frey, Norbert, Lugenbiel, Patrick, Thomas, Dierk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530285/
https://www.ncbi.nlm.nih.gov/pubmed/37762145
http://dx.doi.org/10.3390/ijms241813842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530285/
https://www.ncbi.nlm.nih.gov/pubmed/37762145
http://dx.doi.org/10.3390/ijms241813842

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