α-Bisabolol, a Dietary Sesquiterpene, Attenuates Doxorubicin-Induced Acute Cardiotoxicity in Rats by Inhibiting Cellular Signaling Pathways, Nrf2/Keap-1/HO-1, Akt/mTOR/GSK-3β, NF-κB/p38/MAPK, and NLRP3 Inflammasomes Regulating Oxidative Stress and Inflammatory Cascades

Cancer chemotherapy with doxorubicin (DOX) may have multiorgan toxicities including cardiotoxicity, and this is one of the major limitations of its clinical use. The present study aimed to evaluate the cardioprotective role of α-Bisabolol (BSB) in DOX-induced acute cardiotoxicity in rats and the und...

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Detalles Bibliográficos
Autores principales: Nagoor Meeran, Mohamed Fizur, Arunachalam, Seenipandi, Azimullah, Sheikh, Saraswathiamma, Dhanya, Albawardi, Alia, Almarzooqi, Saeeda, Jha, Niraj Kumar, Subramanya, Sandeep, Beiram, Rami, Ojha, Shreesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530367/
https://www.ncbi.nlm.nih.gov/pubmed/37762315
http://dx.doi.org/10.3390/ijms241814013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530367/
https://www.ncbi.nlm.nih.gov/pubmed/37762315
http://dx.doi.org/10.3390/ijms241814013

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