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Ortho-Selective amination of arene carboxylic acids via rearrangement of acyl O-hydroxylamines

Direct amination of arene C–H bonds is an attractive disconnection to form aniline-derived building blocks. This transformation presents significant practical challenges; classical methods for ortho-selective amination require strongly acidic or forcing conditions, while contemporary catalytic proce...

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Detalles Bibliográficos
Autores principales: Gillespie, James E., Lam, Nelson Y. S., Phipps, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530477/
https://www.ncbi.nlm.nih.gov/pubmed/37772106
http://dx.doi.org/10.1039/d3sc03293k