rs71327024 Associated with COVID-19 Hospitalization Reduces CXCR6 Promoter Activity in Human CD4(+) T Cells via Disruption of c-Myb Binding

Single-nucleotide polymorphism rs71327024 located in the human 3p21.31 locus has been associated with an elevated risk of hospitalization upon SARS-CoV-2 infection. The 3p21.31 locus contains several genes encoding chemokine receptors potentially relevant to severe COVID-19. In particular, CXCR6, wh...

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Detalles Bibliográficos
Autores principales: Uvarova, Aksinya N., Stasevich, Ekaterina M., Ustiugova, Alina S., Mitkin, Nikita A., Zheremyan, Elina A., Sheetikov, Savely A., Zornikova, Ksenia V., Bogolyubova, Apollinariya V., Rubtsov, Mikhail A., Kulakovskiy, Ivan V., Kuprash, Dmitry V., Korneev, Kirill V., Schwartz, Anton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530726/
https://www.ncbi.nlm.nih.gov/pubmed/37762093
http://dx.doi.org/10.3390/ijms241813790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530726/
https://www.ncbi.nlm.nih.gov/pubmed/37762093
http://dx.doi.org/10.3390/ijms241813790

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