BRCA1 Promoter Hypermethylation in Malignant Breast Tumors and in the Histologically Normal Adjacent Tissues to the Tumors: Exploring Its Potential as a Biomarker and Its Clinical Significance in a Translational Approach

The hypermethylation status of the promoter region of the breast cancer 1 (BRCA1), a well-known tumor suppressor gene, has been extensively investigated in the last two decades as a potential biomarker for breast cancer. In this retrospective study, we investigated the prevalence of BRCA1 promoter m...

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Detalles Bibliográficos
Autores principales: Oubaddou, Yassire, Oukabli, Mohamed, Fenniche, Salma, Elktaibi, Abderrahim, Elochi, Mohamed Reda, Al Bouzidi, Abderrahmane, Qmichou, Zineb, Dakka, Nadia, Diorio, Caroline, Richter, Antje, Bakri, Youssef, Ameziane El Hassani, Rabii
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530732/
https://www.ncbi.nlm.nih.gov/pubmed/37761820
http://dx.doi.org/10.3390/genes14091680

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