Mitigation of Dextran-Sodium-Sulfate-Induced Colitis in Mice through Oral Administration of Microbiome-Derived Inosine and Its Underlying Mechanisms

Background: Colonic and serum inosine are significantly reduced in patients with inflammatory bowel disease (IBD). Methods: This study aimed to explore whether microbiome-derived inosine alleviates colitis and its underlying mechanisms. Results: An inosine intervention effectively improved the clini...

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Detalles Bibliográficos
Autores principales: Guo, Weiling, Tang, Xin, Zhang, Qiuxiang, Zhao, Jianxin, Mao, Bingyong, Zhang, Hao, Cui, Shumao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530753/
https://www.ncbi.nlm.nih.gov/pubmed/37762155
http://dx.doi.org/10.3390/ijms241813852

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