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Inhibition of HSP90 in Driver Oncogene-Defined Lung Adenocarcinoma Cell Lines: Key Proteins Underpinning Therapeutic Efficacy

The use of 90 kDa heat shock protein (HSP90) inhibition as a therapy in lung adenocarcinoma remains limited due to moderate drug efficacy, the emergence of drug resistance, and early tumor recurrence. The main objective of this research is to maximize treatment efficacy in lung adenocarcinoma by ide...

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Detalles Bibliográficos
Autores principales: Marrugal, Ángela, Ferrer, Irene, Quintanal-Villalonga, Álvaro, Ojeda, Laura, Pastor, María Dolores, García-Luján, Ricardo, Carnero, Amancio, Paz-Ares, Luis, Molina-Pinelo, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530904/
https://www.ncbi.nlm.nih.gov/pubmed/37762133
http://dx.doi.org/10.3390/ijms241813830