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VHL L169P Variant Does Not Alter Cellular Hypoxia Tension in Clear Cell Renal Cell Carcinoma

In the current era of tumor genome sequencing, single amino acid missense variants in the von Hippel–Lindau (VHL) tumor suppressor gene are frequently identified in clear cell renal carcinoma (ccRCC). Due to the incomplete knowledge of the structural architecture of VHL protein, the functional signi...

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Detalles Bibliográficos
Autores principales:	Hu, Junhui, Smith, Desmond J., Wu, Lily
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530985/ https://www.ncbi.nlm.nih.gov/pubmed/37762376 http://dx.doi.org/10.3390/ijms241814075

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