Cargando…
Simulating Space Conditions Evokes Different DNA Damage Responses in Immature and Mature Cells of the Human Hematopoietic System
The impact of space radiation and microgravity on DNA damage responses has been discussed controversially, largely due to the variety of model systems engaged. Here, we performed side-by-side analyses of human hematopoietic stem/progenitor cells (HSPC) and peripheral blood lymphocytes (PBL) cultivat...
Autores principales: | Handwerk, Leonie, Schreier, Heike Katrin, Kraft, Daniela, Shreder, Kateryna, Hemmersbach, Ruth, Hauslage, Jens, Bonig, Halvard, Wiesmüller, Lisa, Fournier, Claudia, Rall-Scharpf, Melanie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531023/ https://www.ncbi.nlm.nih.gov/pubmed/37762064 http://dx.doi.org/10.3390/ijms241813761 |
Ejemplares similares
-
Hematopoietic-Extrinsic Cues Dictate Circadian Redistribution of Mature and Immature Hematopoietic Cells in Blood and Spleen
por: Stenzinger, Miriam, et al.
Publicado: (2019) -
Impact of Charged Particle Exposure on Homologous DNA Double-Strand Break Repair in Human Blood-Derived Cells
por: Rall, Melanie, et al.
Publicado: (2015) -
Albumin Modifies Responses to Hematopoietic Stem Cell Mobilizing Agents in Mice
por: Danner, Eva, et al.
Publicado: (2019) -
Pyrocystis noctiluca represents an excellent bioassay for shear forces induced in ground-based microgravity simulators (clinostat and random positioning machine)
por: Hauslage, Jens, et al.
Publicado: (2017) -
p53 isoforms differentially impact on the POLι dependent DNA damage tolerance pathway
por: Guo, Yitian, et al.
Publicado: (2021)