Human α-Defensin 5(1–9) and Human β-Defensin 2 Improve Metabolic Parameters and Gut Barrier Function in Mice Fed a Western-Style Diet

Obesity and metabolic comorbidities are associated with gut permeability. While high-fructose and Western-style diet (WSD) disrupt intestinal barrier function, oral administration of human α-defensin 5 (HD5) and β-defensin 2 (hBD2) is believed to improve intestinal integrity and metabolic disorders....

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Autores principales: Filipe Rosa, Louisa, Rings, Andreas, Stolzer, Iris, Koeninger, Louis, Wehkamp, Jan, Beisner, Julia, Günther, Claudia, Nordkild, Peter, Jensen, Benjamin A. H., Bischoff, Stephan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531064/
https://www.ncbi.nlm.nih.gov/pubmed/37762180
http://dx.doi.org/10.3390/ijms241813878

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