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Non-Random Enrichment of Single-Nucleotide Polymorphisms Associated with Clopidogrel Resistance within Risk Loci Linked to the Severity of Underlying Cardiovascular Diseases: The Role of Admixture
Cardiovascular disease (CVD) is one of the leading causes of death in Puerto Rico, where clopidogrel is commonly prescribed to prevent ischemic events. Genetic contributors to both a poor clopidogrel response and the severity of CVD have been identified mainly in Europeans. However, the non-random e...
Autores principales: | Monero-Paredes, Mariangeli, Feliu-Maldonado, Roberto, Carrasquillo-Carrion, Kelvin, Gonzalez, Pablo, Rogozin, Igor B., Roche-Lima, Abiel, Duconge, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531115/ https://www.ncbi.nlm.nih.gov/pubmed/37761953 http://dx.doi.org/10.3390/genes14091813 |
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