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APPA Increases Lifespan and Stress Resistance via Lipid Metabolism and Insulin/IGF-1 Signal Pathway in Caenorhabditis elegans

Animal studies have proven that 1-acetyl-5-phenyl-1H-pyrrol-3-yl acetate (APPA) is a powerful antioxidant as a novel aldose reductase inhibitor independently synthesized by our laboratory; however, there is no current information on APPA’s anti-aging mechanism. Therefore, this study examined the imp...

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Detalles Bibliográficos
Autores principales: Wang, Shiyao, Lin, Dongfa, Cao, Jiaofei, Wang, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531162/
https://www.ncbi.nlm.nih.gov/pubmed/37761985
http://dx.doi.org/10.3390/ijms241813682