Serum levels of fibrogenesis biomarkers reveal distinct endotypes predictive of response to weight loss in advanced nonalcoholic fatty liver disease

BACKGROUND: NAFLD is associated with activation of fibroblasts and hepatic fibrosis. Substantial patient heterogeneity exists, so it remains challenging to risk-stratify patients. We hypothesized that the amount of fibroblast activity, as assessed by circulating biomarkers of collagen formation, can...

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Detalles Bibliográficos
Autores principales: Karsdal, Morten A., Hallsworth, Kate, Scragg, Jadine, Leeming, Diana J., Villesen, Ida F., Avery, Leah, Haigh, Laura, Govaere, Olivier, Wichmann, Sarah, Taylor, Guy, Cassidy, Sophie, McPherson, Stuart, Anstee, Quentin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531192/
https://www.ncbi.nlm.nih.gov/pubmed/37756043
http://dx.doi.org/10.1097/HC9.0000000000000254

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