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Beyond genome-wide association studies: Investigating the role of noncoding regulatory elements in primary sclerosing cholangitis

BACKGROUND: Genome-wide association studies (GWAS) have identified 30 risk loci for primary sclerosing cholangitis (PSC). Variants within these loci are found predominantly in noncoding regions of DNA making their mechanisms of conferring risk hard to define. Epigenomic studies have shown noncoding...

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Detalles Bibliográficos
Autores principales:	Pratt, Henry E., Wu, Tong, Elhajjajy, Shaimae, Zhou, Jeffrey, Fitzgerald, Kate, Fazzio, Tom, Weng, Zhiping, Pratt, Daniel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531193/ https://www.ncbi.nlm.nih.gov/pubmed/37756045 http://dx.doi.org/10.1097/HC9.0000000000000242

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