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The Inhibition of the FGFR/PI3K/Akt Axis by AZD4547 Disrupts the Proangiogenic Microenvironment and Vasculogenic Mimicry Arising from the Interplay between Endothelial and Triple-Negative Breast Cancer Cells

Vasculogenic mimicry (VM), a process in which aggressive cancer cells form tube-like structures, plays a crucial role in providing nutrients and escape routes. Highly plastic tumor cells, such as those with the triple-negative breast cancer (TNBC) phenotype, can develop VM. However, little is known...

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Detalles Bibliográficos
Autores principales: Morales-Guadarrama, Gabriela, Méndez-Pérez, Edgar A., García-Quiroz, Janice, Avila, Euclides, Ibarra-Sánchez, María J., Esparza-López, José, García-Becerra, Rocío, Larrea, Fernando, Díaz, Lorenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531243/
https://www.ncbi.nlm.nih.gov/pubmed/37762073
http://dx.doi.org/10.3390/ijms241813770

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