The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases

This review highlights the complex role of fatty acid β-oxidation in brain metabolism. It demonstrates the fundamental importance of fatty acid degradation as a fuel in energy balance and as an essential component in lipid homeostasis, brain aging, and neurodegenerative disorders.

Detalles Bibliográficos
Autores principales: Szrok-Jurga, Sylwia, Turyn, Jacek, Hebanowska, Areta, Swierczynski, Julian, Czumaj, Aleksandra, Sledzinski, Tomasz, Stelmanska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531288/
https://www.ncbi.nlm.nih.gov/pubmed/37762279
http://dx.doi.org/10.3390/ijms241813977
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author Szrok-Jurga, Sylwia
Turyn, Jacek
Hebanowska, Areta
Swierczynski, Julian
Czumaj, Aleksandra
Sledzinski, Tomasz
Stelmanska, Ewa
author_facet Szrok-Jurga, Sylwia
Turyn, Jacek
Hebanowska, Areta
Swierczynski, Julian
Czumaj, Aleksandra
Sledzinski, Tomasz
Stelmanska, Ewa
author_sort Szrok-Jurga, Sylwia
collection PubMed
description This review highlights the complex role of fatty acid β-oxidation in brain metabolism. It demonstrates the fundamental importance of fatty acid degradation as a fuel in energy balance and as an essential component in lipid homeostasis, brain aging, and neurodegenerative disorders.
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spelling pubmed-105312882023-09-28 The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases Szrok-Jurga, Sylwia Turyn, Jacek Hebanowska, Areta Swierczynski, Julian Czumaj, Aleksandra Sledzinski, Tomasz Stelmanska, Ewa Int J Mol Sci Review This review highlights the complex role of fatty acid β-oxidation in brain metabolism. It demonstrates the fundamental importance of fatty acid degradation as a fuel in energy balance and as an essential component in lipid homeostasis, brain aging, and neurodegenerative disorders. MDPI 2023-09-12 /pmc/articles/PMC10531288/ /pubmed/37762279 http://dx.doi.org/10.3390/ijms241813977 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Szrok-Jurga, Sylwia
Turyn, Jacek
Hebanowska, Areta
Swierczynski, Julian
Czumaj, Aleksandra
Sledzinski, Tomasz
Stelmanska, Ewa
The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases
title The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases
title_full The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases
title_fullStr The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases
title_full_unstemmed The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases
title_short The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases
title_sort role of acyl-coa β-oxidation in brain metabolism and neurodegenerative diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531288/
https://www.ncbi.nlm.nih.gov/pubmed/37762279
http://dx.doi.org/10.3390/ijms241813977
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