USP7 Inhibition Suppresses Neuroblastoma Growth via Induction of p53-Mediated Apoptosis and EZH2 and N-Myc Downregulation

Neuroblastoma (NB) is a pediatric malignancy originating from neural crest cells of the sympathetic nervous system that accounts for 15% of all pediatric cancer deaths. Despite advances in treatment, high-risk NB remains difficult to cure, highlighting the need for novel therapeutic approaches. Ubiq...

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Detalles Bibliográficos
Autores principales: Le Clorennec, Christophe, Lee, Karen, Huo, Yuchen, Zage, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531325/
https://www.ncbi.nlm.nih.gov/pubmed/37762082
http://dx.doi.org/10.3390/ijms241813780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531325/
https://www.ncbi.nlm.nih.gov/pubmed/37762082
http://dx.doi.org/10.3390/ijms241813780

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