Recovering What Matters: High Protein Recovery after Endotoxin Removal from LPS-Contaminated Formulations Using Novel Anti-Lipid A Antibody Microparticle Conjugates

Endotoxins or lipopolysaccharides (LPS), found in the outer membrane of Gram-negative bacterial cell walls, can stimulate the human innate immune system, leading to life-threatening symptoms. Therefore, regulatory limits for endotoxin content apply to injectable pharmaceuticals, and excess LPS must...

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Detalles Bibliográficos
Autores principales: Casonato Melo, Cristiane, Fux, Alexandra C., Himly, Martin, Bastús, Neus G., Schlahsa, Laura, Siewert, Christiane, Puntes, Victor, Duschl, Albert, Gessner, Isabel, Fauerbach, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531372/
https://www.ncbi.nlm.nih.gov/pubmed/37762274
http://dx.doi.org/10.3390/ijms241813971

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