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Anatomic Variations of Renal Arteries as an Important Factor in the Effectiveness of Renal Denervation in Resistant Hypertension
Hypertension remains the leading cause of death worldwide. Despite advances in drug-based treatment, many patients do not achieve target blood pressure. In recent years, there has been an increased interest in invasive hypertension treatment methods. Long-term effects and factors affecting renal den...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531508/ https://www.ncbi.nlm.nih.gov/pubmed/37754800 http://dx.doi.org/10.3390/jcdd10090371 |
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author | Kasprzycki, Karol Petkow-Dimitrow, Paweł Krawczyk-Ożóg, Agata Bartuś, Stanisław Rajtar-Salwa, Renata |
author_facet | Kasprzycki, Karol Petkow-Dimitrow, Paweł Krawczyk-Ożóg, Agata Bartuś, Stanisław Rajtar-Salwa, Renata |
author_sort | Kasprzycki, Karol |
collection | PubMed |
description | Hypertension remains the leading cause of death worldwide. Despite advances in drug-based treatment, many patients do not achieve target blood pressure. In recent years, there has been an increased interest in invasive hypertension treatment methods. Long-term effects and factors affecting renal denervation effectiveness are still under investigation. Some investigators found that the renal arteries’ morphology is crucial in renal denervation effectiveness. Accessory renal arteries occur in 20–30% of the population and even more frequently in patients with resistant hypertension. Diversity in renal vascularization and innervation may complicate the renal denervation procedure and increase the number of people who will not benefit from treatment. Based on previous studies, it has been shown that the presence of accessory renal arteries, and in particular, the lack of their complete denervation, reduces the procedure’s effectiveness. The following review presents the anatomical assessment of the renal arteries, emphasizing the importance of imaging tests. Examples of imaging and denervation methods to optimize the procedure are presented. The development of new-generation catheters and the advancement in knowledge of renal arteries anatomy may improve the effectiveness of treatment and reduce the number of patients who do not respond to treatment. |
format | Online Article Text |
id | pubmed-10531508 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105315082023-09-28 Anatomic Variations of Renal Arteries as an Important Factor in the Effectiveness of Renal Denervation in Resistant Hypertension Kasprzycki, Karol Petkow-Dimitrow, Paweł Krawczyk-Ożóg, Agata Bartuś, Stanisław Rajtar-Salwa, Renata J Cardiovasc Dev Dis Review Hypertension remains the leading cause of death worldwide. Despite advances in drug-based treatment, many patients do not achieve target blood pressure. In recent years, there has been an increased interest in invasive hypertension treatment methods. Long-term effects and factors affecting renal denervation effectiveness are still under investigation. Some investigators found that the renal arteries’ morphology is crucial in renal denervation effectiveness. Accessory renal arteries occur in 20–30% of the population and even more frequently in patients with resistant hypertension. Diversity in renal vascularization and innervation may complicate the renal denervation procedure and increase the number of people who will not benefit from treatment. Based on previous studies, it has been shown that the presence of accessory renal arteries, and in particular, the lack of their complete denervation, reduces the procedure’s effectiveness. The following review presents the anatomical assessment of the renal arteries, emphasizing the importance of imaging tests. Examples of imaging and denervation methods to optimize the procedure are presented. The development of new-generation catheters and the advancement in knowledge of renal arteries anatomy may improve the effectiveness of treatment and reduce the number of patients who do not respond to treatment. MDPI 2023-08-29 /pmc/articles/PMC10531508/ /pubmed/37754800 http://dx.doi.org/10.3390/jcdd10090371 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kasprzycki, Karol Petkow-Dimitrow, Paweł Krawczyk-Ożóg, Agata Bartuś, Stanisław Rajtar-Salwa, Renata Anatomic Variations of Renal Arteries as an Important Factor in the Effectiveness of Renal Denervation in Resistant Hypertension |
title | Anatomic Variations of Renal Arteries as an Important Factor in the Effectiveness of Renal Denervation in Resistant Hypertension |
title_full | Anatomic Variations of Renal Arteries as an Important Factor in the Effectiveness of Renal Denervation in Resistant Hypertension |
title_fullStr | Anatomic Variations of Renal Arteries as an Important Factor in the Effectiveness of Renal Denervation in Resistant Hypertension |
title_full_unstemmed | Anatomic Variations of Renal Arteries as an Important Factor in the Effectiveness of Renal Denervation in Resistant Hypertension |
title_short | Anatomic Variations of Renal Arteries as an Important Factor in the Effectiveness of Renal Denervation in Resistant Hypertension |
title_sort | anatomic variations of renal arteries as an important factor in the effectiveness of renal denervation in resistant hypertension |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531508/ https://www.ncbi.nlm.nih.gov/pubmed/37754800 http://dx.doi.org/10.3390/jcdd10090371 |
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