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Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease

(1) Background: To identify the association between the presence or absence of a raphe and aortic valve dysfunction, as well as the presence of aortopathy in patients with a bicuspid aortic valve (BAV); (2) Methods: This retrospective study enrolled 312 participants (mean (SD) age, 52.7 (14.3) years...

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Autores principales: Zhang, Yu, Choi, Bo Hwa, Chee, Hyun Keun, Kim, Jun Seok, Ko, Sung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531753/
https://www.ncbi.nlm.nih.gov/pubmed/37754801
http://dx.doi.org/10.3390/jcdd10090372
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author Zhang, Yu
Choi, Bo Hwa
Chee, Hyun Keun
Kim, Jun Seok
Ko, Sung Min
author_facet Zhang, Yu
Choi, Bo Hwa
Chee, Hyun Keun
Kim, Jun Seok
Ko, Sung Min
author_sort Zhang, Yu
collection PubMed
description (1) Background: To identify the association between the presence or absence of a raphe and aortic valve dysfunction, as well as the presence of aortopathy in patients with a bicuspid aortic valve (BAV); (2) Methods: This retrospective study enrolled 312 participants (mean (SD) age, 52.7 (14.3) years; 227 men (72.8%)) with BAV. The BAVs were divided into those with the presence (raphe+) or absence (raphe−) of a raphe. Valvular function was classified as normal, aortic regurgitation (AR), or aortic stenosis (AS) using TTE. The pattern of BAV aortopathy was determined by the presence of dilatation at the sinus of Valsalva and the middle ascending aorta using CCT; (3) Results: BAVs with raphe+ had a higher prevalence of AR (148 (79.5%) vs. 48 (37.8%), p < 0.001), but a lower prevalence of AS (90 (48.6%) vs. 99 (78.0%), p < 0.001) compared with those with raphe−. The types of BAV aortopathy were significantly different (p = 0.021) according to those with BAV–raphe+ and BAV–raphe−; (4) Conclusions: The presence of a raphe was significantly associated with a higher prevalence of AR, but a lower prevalence of AS and combined dilatation of the aortic root and middle ascending aorta. The presence of a raphe was an independent determinant of AR.
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spelling pubmed-105317532023-09-28 Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease Zhang, Yu Choi, Bo Hwa Chee, Hyun Keun Kim, Jun Seok Ko, Sung Min J Cardiovasc Dev Dis Article (1) Background: To identify the association between the presence or absence of a raphe and aortic valve dysfunction, as well as the presence of aortopathy in patients with a bicuspid aortic valve (BAV); (2) Methods: This retrospective study enrolled 312 participants (mean (SD) age, 52.7 (14.3) years; 227 men (72.8%)) with BAV. The BAVs were divided into those with the presence (raphe+) or absence (raphe−) of a raphe. Valvular function was classified as normal, aortic regurgitation (AR), or aortic stenosis (AS) using TTE. The pattern of BAV aortopathy was determined by the presence of dilatation at the sinus of Valsalva and the middle ascending aorta using CCT; (3) Results: BAVs with raphe+ had a higher prevalence of AR (148 (79.5%) vs. 48 (37.8%), p < 0.001), but a lower prevalence of AS (90 (48.6%) vs. 99 (78.0%), p < 0.001) compared with those with raphe−. The types of BAV aortopathy were significantly different (p = 0.021) according to those with BAV–raphe+ and BAV–raphe−; (4) Conclusions: The presence of a raphe was significantly associated with a higher prevalence of AR, but a lower prevalence of AS and combined dilatation of the aortic root and middle ascending aorta. The presence of a raphe was an independent determinant of AR. MDPI 2023-08-31 /pmc/articles/PMC10531753/ /pubmed/37754801 http://dx.doi.org/10.3390/jcdd10090372 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Yu
Choi, Bo Hwa
Chee, Hyun Keun
Kim, Jun Seok
Ko, Sung Min
Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease
title Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease
title_full Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease
title_fullStr Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease
title_full_unstemmed Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease
title_short Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease
title_sort aortic valve dysfunction and aortopathy based on the presence of raphe in patients with bicuspid aortic valve disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531753/
https://www.ncbi.nlm.nih.gov/pubmed/37754801
http://dx.doi.org/10.3390/jcdd10090372
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