Selective Block of Upregulated Kv1.3 Potassium Channels in ON-Bipolar Cells of the Blind Retina Enhances Optogenetically Restored Signaling

Loss of photoreceptors in retinal degenerative diseases also impacts the inner retina: bipolar cell dendrites retract, neurons rewire, and protein expression changes. ON-bipolar cells (OBCs) represent an attractive target for optogenetic vision restoration. However, the above-described maladaptation...

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Detalles Bibliográficos
Autores principales: Schilardi, Giulia, Kralik, Jakub, Kleinlogel, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531754/
https://www.ncbi.nlm.nih.gov/pubmed/37762510
http://dx.doi.org/10.3390/ijms241814207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531754/
https://www.ncbi.nlm.nih.gov/pubmed/37762510
http://dx.doi.org/10.3390/ijms241814207

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