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Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in Adipocytes
Type 2 diabetes mellitus is a chronic metabolic disease with no cure. Adipose tissue is a major site of systemic insulin resistance. Sortilin is a central component of the glucose transporter -Glut4 storage vesicles (GSV) which translocate to the plasma membrane to uptake glucose from circulation. H...
Autores principales: | Lui, Ashley, Patel, Rekha S., Krause-Hauch, Meredith, Sparks, Robert P., Patel, Niketa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531797/ https://www.ncbi.nlm.nih.gov/pubmed/37762628 http://dx.doi.org/10.3390/ijms241814324 |
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