Targeted Radiation Exposure Induces Accelerated Aortic Valve Remodeling in ApoE(−/−) Mice

Thoracic radiation therapy may result in accelerated atherosclerosis and in late aortic valve stenosis (AS). In this study, we assessed the feasibility of inducing radiation-induced AS using a targeted aortic valve irradiation (10 or 20 Grays) in two groups of C57Bl6/J (WT) and ApoE(−/−) mice compar...

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Detalles Bibliográficos
Autores principales: Rucher, Guillaume, Prigent, Kevin, Simard, Christophe, Frelin, Anne-Marie, Coquemont-Guyot, Maëlle, Elie, Nicolas, Delcroix, Nicolas, Perzo, Nicolas, Guinamard, Romain, Berger, Ludovic, Manrique, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531867/
https://www.ncbi.nlm.nih.gov/pubmed/37762794
http://dx.doi.org/10.3390/jcm12185854

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