PLK1 Regulates MicroRNA Biogenesis through Drosha Phosphorylation

Polo-Like Kinase 1 (PLK1), a key mediator of cell-cycle progression, is associated with poor prognosis and is a therapeutic target in a number of malignancies. Putative phosphorylation sites for PLK1 have been identified on Drosha, the main catalytic component of the microprocessor responsible for m...

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Detalles Bibliográficos
Autores principales: Fletcher, Claire Emily, Taylor, Molly Ann, Bevan, Charlotte Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531876/
https://www.ncbi.nlm.nih.gov/pubmed/37762595
http://dx.doi.org/10.3390/ijms241814290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531876/
https://www.ncbi.nlm.nih.gov/pubmed/37762595
http://dx.doi.org/10.3390/ijms241814290

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