Uridine as a Regulator of Functional and Ultrastructural Changes in the Brain of Rats in a Model of 6-OHDA-Induced Parkinson’s Disease

Using a model of Parkinson’s disease (PD) induced by the bilateral injection of neurotoxin 6-hydroxydopamine (6-OHDA) into rat brain substantia nigra (SN), we showed uridine to exert a protective effect associated with activation of the mitochondrial ATP-dependent potassium (mitoK-ATP) channel. Inje...

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Detalles Bibliográficos
Autores principales: Uspalenko, Nina I., Mosentsov, Alexei A., Khmil, Natalia V., Pavlik, Lyubov L., Belosludtseva, Natalia V., Khunderyakova, Natalia V., Shigaeva, Maria I., Medvedeva, Vasilisa P., Malkov, Anton E., Kitchigina, Valentina F., Mironova, Galina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531918/
https://www.ncbi.nlm.nih.gov/pubmed/37762607
http://dx.doi.org/10.3390/ijms241814304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531918/
https://www.ncbi.nlm.nih.gov/pubmed/37762607
http://dx.doi.org/10.3390/ijms241814304

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