SYNE1 Mutation Is Associated with Increased Tumor Mutation Burden and Immune Cell Infiltration in Ovarian Cancer

SYNE1, a nuclear envelope protein critical for cellular structure and signaling, is downregulated in numerous malignancies. SYNE1 alterations are found in 10% of gynecologic malignancies and 5% of epithelial ovarian cancers. Previous studies demonstrated an association between SYNE1 mutation, increa...

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Detalles Bibliográficos
Autores principales: Harbin, Laura M., Lin, Nan, Ueland, Frederick R., Kolesar, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531966/
https://www.ncbi.nlm.nih.gov/pubmed/37762518
http://dx.doi.org/10.3390/ijms241814212

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