Cargando…

Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls

Background: Comparing intraocular pressure (IOP) changes (ΔIOP) between obese subjects and non-obese controls in relation to different positions: standing, sitting, supine. Methods: the IOP was measured in both obese patients and non-obese controls groups with Tono-Pen AVIA in different positions fo...

Descripción completa

Detalles Bibliográficos
Autores principales: De Bernardo, Maddalena, Pilone, Vincenzo, Di Paola, Ilenia, Cione, Ferdinando, Cembalo, Giovanni, Calabrese, Pietro, Rosa, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531973/
https://www.ncbi.nlm.nih.gov/pubmed/37762825
http://dx.doi.org/10.3390/jcm12185883
_version_ 1785111846010748928
author De Bernardo, Maddalena
Pilone, Vincenzo
Di Paola, Ilenia
Cione, Ferdinando
Cembalo, Giovanni
Calabrese, Pietro
Rosa, Nicola
author_facet De Bernardo, Maddalena
Pilone, Vincenzo
Di Paola, Ilenia
Cione, Ferdinando
Cembalo, Giovanni
Calabrese, Pietro
Rosa, Nicola
author_sort De Bernardo, Maddalena
collection PubMed
description Background: Comparing intraocular pressure (IOP) changes (ΔIOP) between obese subjects and non-obese controls in relation to different positions: standing, sitting, supine. Methods: the IOP was measured in both obese patients and non-obese controls groups with Tono-Pen AVIA in different positions following this sequence: after 5 min (5′) in the standing position, sitting, supine, supine after 5 min (supine 5′) and immediately after standing. ΔIOP values obtained comparing all positions were, therefore, evaluated. Results: 92 eyes of 46 obese subjects aged between 18 and 59 years (mean 38.07 ± 11.51 years) and of a Body Mass Index (BMI) between 31.84 and 60.65 (mean 41.84 ± 7.05) were evaluated. A total of 48 eyes of 24 non-obese controls aged between 23 and 55 (mean 35.21 ± 11.96 years) and of a BMI between 18.20 and 26.79 (mean 21.04 ± 2.36) were also recruited. In obese subjects, there were statistically significant differences between the IOP in the supine position and the supine positions 5′ with all other IOP measurements (p < 0.05). There were statistically significant differences between ΔIOP in both supine positions and prolonged standing positions obtained by obese subjects and non-obese controls (p < 0.05). Conclusions: In obese subjects, there is a statistically significant increase in IOP in the supine positions that is significantly greater than the non-obese population. BMI is weakly correlated with IOP and ΔIOP in postural changes.
format Online
Article
Text
id pubmed-10531973
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-105319732023-09-28 Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls De Bernardo, Maddalena Pilone, Vincenzo Di Paola, Ilenia Cione, Ferdinando Cembalo, Giovanni Calabrese, Pietro Rosa, Nicola J Clin Med Article Background: Comparing intraocular pressure (IOP) changes (ΔIOP) between obese subjects and non-obese controls in relation to different positions: standing, sitting, supine. Methods: the IOP was measured in both obese patients and non-obese controls groups with Tono-Pen AVIA in different positions following this sequence: after 5 min (5′) in the standing position, sitting, supine, supine after 5 min (supine 5′) and immediately after standing. ΔIOP values obtained comparing all positions were, therefore, evaluated. Results: 92 eyes of 46 obese subjects aged between 18 and 59 years (mean 38.07 ± 11.51 years) and of a Body Mass Index (BMI) between 31.84 and 60.65 (mean 41.84 ± 7.05) were evaluated. A total of 48 eyes of 24 non-obese controls aged between 23 and 55 (mean 35.21 ± 11.96 years) and of a BMI between 18.20 and 26.79 (mean 21.04 ± 2.36) were also recruited. In obese subjects, there were statistically significant differences between the IOP in the supine position and the supine positions 5′ with all other IOP measurements (p < 0.05). There were statistically significant differences between ΔIOP in both supine positions and prolonged standing positions obtained by obese subjects and non-obese controls (p < 0.05). Conclusions: In obese subjects, there is a statistically significant increase in IOP in the supine positions that is significantly greater than the non-obese population. BMI is weakly correlated with IOP and ΔIOP in postural changes. MDPI 2023-09-10 /pmc/articles/PMC10531973/ /pubmed/37762825 http://dx.doi.org/10.3390/jcm12185883 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
De Bernardo, Maddalena
Pilone, Vincenzo
Di Paola, Ilenia
Cione, Ferdinando
Cembalo, Giovanni
Calabrese, Pietro
Rosa, Nicola
Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls
title Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls
title_full Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls
title_fullStr Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls
title_full_unstemmed Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls
title_short Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls
title_sort intraocular pressure variations in postural changes: comparison between obese and non-obese controls
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531973/
https://www.ncbi.nlm.nih.gov/pubmed/37762825
http://dx.doi.org/10.3390/jcm12185883
work_keys_str_mv AT debernardomaddalena intraocularpressurevariationsinposturalchangescomparisonbetweenobeseandnonobesecontrols
AT pilonevincenzo intraocularpressurevariationsinposturalchangescomparisonbetweenobeseandnonobesecontrols
AT dipaolailenia intraocularpressurevariationsinposturalchangescomparisonbetweenobeseandnonobesecontrols
AT cioneferdinando intraocularpressurevariationsinposturalchangescomparisonbetweenobeseandnonobesecontrols
AT cembalogiovanni intraocularpressurevariationsinposturalchangescomparisonbetweenobeseandnonobesecontrols
AT calabresepietro intraocularpressurevariationsinposturalchangescomparisonbetweenobeseandnonobesecontrols
AT rosanicola intraocularpressurevariationsinposturalchangescomparisonbetweenobeseandnonobesecontrols