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Modeling Myotonic Dystrophy Type 2 Using Drosophila melanogaster

Myotonic dystrophy 2 (DM2) is a genetic multi-systemic disease primarily affecting skeletal muscle. It is caused by CCTGn expansion in intron 1 of the CNBP gene, which encodes a zinc finger protein. DM2 disease has been successfully modeled in Drosophila melanogaster, allowing the identification and...

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Detalles Bibliográficos
Autores principales: Marzullo, Marta, Coni, Sonia, De Simone, Assia, Canettieri, Gianluca, Ciapponi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532015/
https://www.ncbi.nlm.nih.gov/pubmed/37762484
http://dx.doi.org/10.3390/ijms241814182

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