Cargando…

The Phytochemical Profiling, In Vitro Antioxidant, and Hepatoprotective Activity of Prenanthes purpurea L. and Caffeoylquinic Acids in Diclofenac-Induced Hepatotoxicity on HEP-G2 Cells

Oxidative stress is a common phenomenon of many liver disorders; it both affects patient survival and directly influences the applicability, effectiveness, and toxicity of drugs. In the pursuit of reliable natural remedies for hepatoprotection, this study reports on the complete phytochemical charac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mihaylova, Rositsa, Gevrenova, Reneta, Stefanova, Alexandra, Zheleva-Dimitrova, Dimitrina, Balabanova, Vessela, Zengin, Gökhan, Simeonova, Rumyana, Momekov, Georgi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532168/ https://www.ncbi.nlm.nih.gov/pubmed/37762452 http://dx.doi.org/10.3390/ijms241814148

Ejemplares similares

Antioxidant and Hepatoprotective Potential of Echinops ritro L. Extracts on Induced Oxidative Stress In Vitro/In Vivo
por: Zheleva-Dimitrova, Dimitrina, et al.
Publicado: (2023)

Phytochemical Profiling, Antioxidant and Cognitive-Enhancing Effect of Helichrysum italicum ssp. italicum (Roth) G. Don (Asteraceae)
por: Gevrenova, Reneta, et al.
Publicado: (2023)

Metabolite profiling and bioactivity of Cicerbita alpina (L.) Wallr. (Asteraceae, Cichorieae)
por: Zheleva-Dimitrova, Dimitrina, et al.
Publicado: (2023)

Chemophenetic Approach to Selected Senecioneae Species, Combining Morphometric and UHPLC-HRMS Analyses
por: Voynikov, Yulian, et al.
Publicado: (2023)

Chemometrics-based Approach in Analysis of Arnicae flos
por: Zheleva-Dimitrova, Dimitrina Zh., et al.
Publicado: (2015)

Flavonoid profiles of three Bupleurum species and in vitro hepatoprotective of activity Bupleurum flavum Forsk.
por: Gevrenova, Reneta, et al.
Publicado: (2015)

UHPLC-Orbitrap-MS Tentative Identification of 51 Oleraceins (Cyclo-Dopa Amides) in Portulaca oleracea L. Cluster Analysis and MS(2) Filtering by Mass Difference
por: Voynikov, Yulian, et al.
Publicado: (2021)

An In-Depth Study of Metabolite Profile and Biological Potential of Tanacetum balsamita L. (Costmary)
por: Gevrenova, Reneta, et al.
Publicado: (2022)

Innovative Biochemometric Approach to the Metabolite and Biological Profiling of the Balkan Thistle (Cirsium appendiculatum Griseb.), Asteraceae
por: Zheleva-Dimitrova, Dimitrina, et al.
Publicado: (2021)

A Comparative Study on UHPLC-HRMS Profiles and Biological Activities of Inula sarana Different Extracts and Its Beta-Cyclodextrin Complex: Effective Insights for Novel Applications
por: Zengin, Gokhan, et al.
Publicado: (2023)

Quantitative Characterization of Arnicae flos by RP-HPLC-UV and NIR Spectroscopy
por: Ivanova, Daniela, et al.
Publicado: (2018)

Orbitrap Mass Spectrometry-Based Profiling of Secondary Metabolites in Two Unexplored Eminium Species and Bioactivity Potential
por: Babacan, Ebru Yuce, et al.
Publicado: (2023)

Benzophenones from Hypericum elegans with antioxidant and acetylcholinesterase inhibitory potential
por: Zheleva-Dimitrova, Dimitrina, et al.
Publicado: (2013)

UHPLC-MS Characterization and Biological Insights of Different Solvent Extracts of Two Achillea Species (A. aleppica and A. santolinoides) from Turkey
por: Gevrenova, Reneta, et al.
Publicado: (2021)

Antimicrobial and Antioxidant Potential of Scenedesmus obliquus Microalgae in the Context of Integral Biorefinery Concept
por: Zaharieva, Maya Margaritova, et al.
Publicado: (2022)

An In-Depth Study on the Metabolite Profile and Biological Properties of Primula auriculata Extracts: A Fascinating Sparkle on the Way from Nature to Functional Applications
por: Kurt-Celep, Inci, et al.
Publicado: (2022)

Hepatoprotective and Antioxidant Effects of Saponarin, Isolated from Gypsophila trichotoma Wend. on Paracetamol-Induced Liver Damage in Rats
por: Simeonova, Rumyana, et al.
Publicado: (2013)

Exploring the Chemical Profiles and Biological Values of Two Spondias Species (S. dulcis and S. mombin): Valuable Sources of Bioactive Natural Products
por: Sinan, Kouadio Ibrahime, et al.
Publicado: (2021)

Which Extraction Solvents and Methods Are More Effective in Terms of Chemical Composition and Biological Activity of Alcea fasciculiflora from Turkey?
por: Ozturk, Refiye Beyza, et al.
Publicado: (2022)

A Novel Galantamine-Curcumin Hybrid as a Potential Multi-Target Agent against Neurodegenerative Disorders
por: Simeonova, Rumyana, et al.
Publicado: (2021)

LC-MS/HRMS Analysis, Anti-Cancer, Anti-Enzymatic and Anti-Oxidant Effects of Boerhavia diffusa Extracts: A Potential Raw Material for Functional Applications
por: Sinan, Kouadio Ibrahime, et al.
Publicado: (2021)

Antioxidant and acetylcholinesterase inhibition properties of Amorpha fruticosa L. and Phytolacca americana L.
por: Zheleva-Dimitrova, Dimitrina Zh.
Publicado: (2013)

Effect of cytisine on some brain and hepatic biochemical parameters in spontaneously hypertensive rats
por: Simeonova, Rumyana, et al.
Publicado: (2010)

Design, Synthesis, In Silico Studies and In Vitro Evaluation of New Indole- and/or Donepezil-like Hybrids as Multitarget-Directed Agents for Alzheimer’s Disease
por: Angelova, Violina T., et al.
Publicado: (2023)

Comprehensive Chemical Profiling and Multidirectional Biological Investigation of Two Wild Anthemis Species (Anthemis tinctoria var. Pallida and A. cretica subsp. tenuiloba): Focus on Neuroprotective Effects
por: Orlando, Giustino, et al.
Publicado: (2019)

Hepatoprotective activity of Tephrosia purpurea against arsenic induced toxicity in rats
por: Gora, Ravuri Halley, et al.
Publicado: (2014)

Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria
por: Zheleva-Dimitrova, Dimitrina, et al.
Publicado: (2010)

Some In Vitro/In Vivo Chemically-Induced Experimental Models of Liver Oxidative Stress in Rats
por: Simeonova, Rumyana, et al.
Publicado: (2014)

Selective Nitric Oxide Synthase Inhibitor 7-Nitroindazole Protects against Cocaine-Induced Oxidative Stress in Rat Brain
por: Vitcheva, Vessela, et al.
Publicado: (2015)

Synthesis and antioxidant activity of some 1-aryl/aralkyl piperazine derivatives with xanthine moiety at N4
por: Andonova, Lily, et al.
Publicado: (2014)

Pyrenebutyrate Pt(IV) Complexes with Nanomolar Anticancer Activity
por: Ahmedova, Anife, et al.
Publicado: (2023)

Hepatoprotective Activity of Methanolic Extract of Bauhinia purpurea Leaves against Paracetamol-Induced Hepatic Damage in Rats
por: Yahya, F., et al.
Publicado: (2013)

Cytoprotective and antioxidant effects of phenolic compounds from Haberlea rhodopensis Friv. (Gesneriaceae)
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2013)

Hepatoprotective and nephroprotective effects of Tessaria integrifolia Ruiz and Pav. on diclofenac-induced toxicity in rats
por: Mendoza-Fernández, Paquito D., et al.
Publicado: (2023)

Assessment of surgical sutures POLYMED(®) by intracutaneous irritation test in rabbits
por: Simeonova, Rumyana, et al.
Publicado: (2013)

Antioxidant, anti-inflammatory and hepatoprotective activities of Terminalia bellirica and its bioactive component ellagic acid against diclofenac induced oxidative stress and hepatotoxicity
por: Gupta, Ashutosh, et al.
Publicado: (2020)

Topical Diclofenac-Induced Hepatotoxicity
por: Delungahawatta, Thilini, et al.
Publicado: (2023)

In Vivo Toxicity, Redox-Modulating Capacity and Intestinal Permeability of Novel Aroylhydrazone Derivatives as Anti-Tuberculosis Agents
por: Valcheva, Violeta, et al.
Publicado: (2022)

Echinacea purpurea
por: Lim, T. K.
Publicado: (2013)

Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors
por: Atanasova, Mariyana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pmpnrdl8oac1np0ubkp8noecci