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A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA

Common variants of the MC1R gene coding the α-melanocyte stimulating hormone receptor are associated with light skin, poor tanning, blond or red hair, and increased melanoma risk, due to pigment-dependent and -independent effects. This complex phenotype is usually attributed to impaired activation o...

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Detalles Bibliográficos
Autores principales: Cerdido, Sonia, Sánchez-Beltrán, José, Lambertos, Ana, Abrisqueta, Marta, Padilla, Lidia, Herraiz, Cecilia, Olivares, Conchi, Jiménez-Cervantes, Celia, García-Borrón, José C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532403/
https://www.ncbi.nlm.nih.gov/pubmed/37762683
http://dx.doi.org/10.3390/ijms241814381