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A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA
Common variants of the MC1R gene coding the α-melanocyte stimulating hormone receptor are associated with light skin, poor tanning, blond or red hair, and increased melanoma risk, due to pigment-dependent and -independent effects. This complex phenotype is usually attributed to impaired activation o...
Autores principales: | Cerdido, Sonia, Sánchez-Beltrán, José, Lambertos, Ana, Abrisqueta, Marta, Padilla, Lidia, Herraiz, Cecilia, Olivares, Conchi, Jiménez-Cervantes, Celia, García-Borrón, José C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532403/ https://www.ncbi.nlm.nih.gov/pubmed/37762683 http://dx.doi.org/10.3390/ijms241814381 |
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