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A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes
Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo they transport is not within a random system....
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532540/ https://www.ncbi.nlm.nih.gov/pubmed/37763246 http://dx.doi.org/10.3390/life13091842 |
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author | Velázquez-Cervantes, Manuel Adrián Benítez-Zeferino, Yazmín Rocío Flores-Pliego, Arturo Helguera-Repetto, Addy Cecilia Meza-Sánchez, David Eduardo Maravillas-Montero, José Luis León-Reyes, Guadalupe Mancilla-Ramírez, Javier Cerna-Cortés, Jorge Francisco Baeza-Ramírez, María Isabel León-Juaárez, Moises |
author_facet | Velázquez-Cervantes, Manuel Adrián Benítez-Zeferino, Yazmín Rocío Flores-Pliego, Arturo Helguera-Repetto, Addy Cecilia Meza-Sánchez, David Eduardo Maravillas-Montero, José Luis León-Reyes, Guadalupe Mancilla-Ramírez, Javier Cerna-Cortés, Jorge Francisco Baeza-Ramírez, María Isabel León-Juaárez, Moises |
author_sort | Velázquez-Cervantes, Manuel Adrián |
collection | PubMed |
description | Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo they transport is not within a random system. In fact, it depends on various molecular signals and the recruitment of proteins that participate in the biogenesis of exosomes. It has also been shown that multiple viruses can recruit these vesicles to transport viral factors such as genomes or proteins. It has been shown that the late domains present in viral proteins are critical for the exosomal selection and biogenesis systems to recognize these viral proteins and introduce them into the exosomes. In this review, the researchers discuss the evidence related to the characterization of these late domains and their role in exosome recruitment during viral infection. |
format | Online Article Text |
id | pubmed-10532540 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105325402023-09-28 A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes Velázquez-Cervantes, Manuel Adrián Benítez-Zeferino, Yazmín Rocío Flores-Pliego, Arturo Helguera-Repetto, Addy Cecilia Meza-Sánchez, David Eduardo Maravillas-Montero, José Luis León-Reyes, Guadalupe Mancilla-Ramírez, Javier Cerna-Cortés, Jorge Francisco Baeza-Ramírez, María Isabel León-Juaárez, Moises Life (Basel) Review Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo they transport is not within a random system. In fact, it depends on various molecular signals and the recruitment of proteins that participate in the biogenesis of exosomes. It has also been shown that multiple viruses can recruit these vesicles to transport viral factors such as genomes or proteins. It has been shown that the late domains present in viral proteins are critical for the exosomal selection and biogenesis systems to recognize these viral proteins and introduce them into the exosomes. In this review, the researchers discuss the evidence related to the characterization of these late domains and their role in exosome recruitment during viral infection. MDPI 2023-08-31 /pmc/articles/PMC10532540/ /pubmed/37763246 http://dx.doi.org/10.3390/life13091842 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Velázquez-Cervantes, Manuel Adrián Benítez-Zeferino, Yazmín Rocío Flores-Pliego, Arturo Helguera-Repetto, Addy Cecilia Meza-Sánchez, David Eduardo Maravillas-Montero, José Luis León-Reyes, Guadalupe Mancilla-Ramírez, Javier Cerna-Cortés, Jorge Francisco Baeza-Ramírez, María Isabel León-Juaárez, Moises A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes |
title | A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes |
title_full | A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes |
title_fullStr | A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes |
title_full_unstemmed | A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes |
title_short | A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes |
title_sort | review study of the participation of late domains in sorting and transport of viral factors to exosomes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532540/ https://www.ncbi.nlm.nih.gov/pubmed/37763246 http://dx.doi.org/10.3390/life13091842 |
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