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A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes

Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo they transport is not within a random system....

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Autores principales: Velázquez-Cervantes, Manuel Adrián, Benítez-Zeferino, Yazmín Rocío, Flores-Pliego, Arturo, Helguera-Repetto, Addy Cecilia, Meza-Sánchez, David Eduardo, Maravillas-Montero, José Luis, León-Reyes, Guadalupe, Mancilla-Ramírez, Javier, Cerna-Cortés, Jorge Francisco, Baeza-Ramírez, María Isabel, León-Juaárez, Moises
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532540/
https://www.ncbi.nlm.nih.gov/pubmed/37763246
http://dx.doi.org/10.3390/life13091842
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author Velázquez-Cervantes, Manuel Adrián
Benítez-Zeferino, Yazmín Rocío
Flores-Pliego, Arturo
Helguera-Repetto, Addy Cecilia
Meza-Sánchez, David Eduardo
Maravillas-Montero, José Luis
León-Reyes, Guadalupe
Mancilla-Ramírez, Javier
Cerna-Cortés, Jorge Francisco
Baeza-Ramírez, María Isabel
León-Juaárez, Moises
author_facet Velázquez-Cervantes, Manuel Adrián
Benítez-Zeferino, Yazmín Rocío
Flores-Pliego, Arturo
Helguera-Repetto, Addy Cecilia
Meza-Sánchez, David Eduardo
Maravillas-Montero, José Luis
León-Reyes, Guadalupe
Mancilla-Ramírez, Javier
Cerna-Cortés, Jorge Francisco
Baeza-Ramírez, María Isabel
León-Juaárez, Moises
author_sort Velázquez-Cervantes, Manuel Adrián
collection PubMed
description Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo they transport is not within a random system. In fact, it depends on various molecular signals and the recruitment of proteins that participate in the biogenesis of exosomes. It has also been shown that multiple viruses can recruit these vesicles to transport viral factors such as genomes or proteins. It has been shown that the late domains present in viral proteins are critical for the exosomal selection and biogenesis systems to recognize these viral proteins and introduce them into the exosomes. In this review, the researchers discuss the evidence related to the characterization of these late domains and their role in exosome recruitment during viral infection.
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spelling pubmed-105325402023-09-28 A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes Velázquez-Cervantes, Manuel Adrián Benítez-Zeferino, Yazmín Rocío Flores-Pliego, Arturo Helguera-Repetto, Addy Cecilia Meza-Sánchez, David Eduardo Maravillas-Montero, José Luis León-Reyes, Guadalupe Mancilla-Ramírez, Javier Cerna-Cortés, Jorge Francisco Baeza-Ramírez, María Isabel León-Juaárez, Moises Life (Basel) Review Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo they transport is not within a random system. In fact, it depends on various molecular signals and the recruitment of proteins that participate in the biogenesis of exosomes. It has also been shown that multiple viruses can recruit these vesicles to transport viral factors such as genomes or proteins. It has been shown that the late domains present in viral proteins are critical for the exosomal selection and biogenesis systems to recognize these viral proteins and introduce them into the exosomes. In this review, the researchers discuss the evidence related to the characterization of these late domains and their role in exosome recruitment during viral infection. MDPI 2023-08-31 /pmc/articles/PMC10532540/ /pubmed/37763246 http://dx.doi.org/10.3390/life13091842 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Velázquez-Cervantes, Manuel Adrián
Benítez-Zeferino, Yazmín Rocío
Flores-Pliego, Arturo
Helguera-Repetto, Addy Cecilia
Meza-Sánchez, David Eduardo
Maravillas-Montero, José Luis
León-Reyes, Guadalupe
Mancilla-Ramírez, Javier
Cerna-Cortés, Jorge Francisco
Baeza-Ramírez, María Isabel
León-Juaárez, Moises
A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes
title A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes
title_full A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes
title_fullStr A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes
title_full_unstemmed A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes
title_short A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes
title_sort review study of the participation of late domains in sorting and transport of viral factors to exosomes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532540/
https://www.ncbi.nlm.nih.gov/pubmed/37763246
http://dx.doi.org/10.3390/life13091842
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