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Becoming aWARE: The Development of a Web-Based Tool for Autism Research and the Environment
A sharp rise in autism spectrum disorder (ASD) prevalence estimates, beginning in the 1990s, suggested factors additional to genetics were at play. This stimulated increased research investment in nongenetic factors, including the study of environmental chemical exposures, diet, nutrition, lifestyle...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532575/ https://www.ncbi.nlm.nih.gov/pubmed/37754843 http://dx.doi.org/10.3390/jox13030031 |
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author | Singh, Anisha Lawler, Cindy P. Walker, Vickie R. Pelch, Katherine E. Garton, Amanda E. Rooney, Andrew A. Haugen, Astrid C. |
author_facet | Singh, Anisha Lawler, Cindy P. Walker, Vickie R. Pelch, Katherine E. Garton, Amanda E. Rooney, Andrew A. Haugen, Astrid C. |
author_sort | Singh, Anisha |
collection | PubMed |
description | A sharp rise in autism spectrum disorder (ASD) prevalence estimates, beginning in the 1990s, suggested factors additional to genetics were at play. This stimulated increased research investment in nongenetic factors, including the study of environmental chemical exposures, diet, nutrition, lifestyle, social factors, and maternal medical conditions. Consequently, both peer- and non-peer-reviewed bodies of evidence investigating environmental contributors to ASD etiology have grown significantly. The heterogeneity in the design and conduct of this research results in an inconclusive and unwieldy ‘virtual stack’ of publications. We propose to develop a Web-based tool for Autism Research and the Environment (aWARE) to comprehensively aggregate and assess these highly variable and often conflicting data. The interactive aWARE tool will use an approach for the development of systematic evidence maps (SEMs) to identify and display all available relevant published evidence, enabling users to explore multiple research questions within the scope of the SEM. Throughout tool development, listening sessions and workshops will be used to seek perspectives from the broader autism community. New evidence will be indexed in the tool annually, which will serve as a living resource to investigate the association between environmental factors and ASD. |
format | Online Article Text |
id | pubmed-10532575 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105325752023-09-28 Becoming aWARE: The Development of a Web-Based Tool for Autism Research and the Environment Singh, Anisha Lawler, Cindy P. Walker, Vickie R. Pelch, Katherine E. Garton, Amanda E. Rooney, Andrew A. Haugen, Astrid C. J Xenobiot Communication A sharp rise in autism spectrum disorder (ASD) prevalence estimates, beginning in the 1990s, suggested factors additional to genetics were at play. This stimulated increased research investment in nongenetic factors, including the study of environmental chemical exposures, diet, nutrition, lifestyle, social factors, and maternal medical conditions. Consequently, both peer- and non-peer-reviewed bodies of evidence investigating environmental contributors to ASD etiology have grown significantly. The heterogeneity in the design and conduct of this research results in an inconclusive and unwieldy ‘virtual stack’ of publications. We propose to develop a Web-based tool for Autism Research and the Environment (aWARE) to comprehensively aggregate and assess these highly variable and often conflicting data. The interactive aWARE tool will use an approach for the development of systematic evidence maps (SEMs) to identify and display all available relevant published evidence, enabling users to explore multiple research questions within the scope of the SEM. Throughout tool development, listening sessions and workshops will be used to seek perspectives from the broader autism community. New evidence will be indexed in the tool annually, which will serve as a living resource to investigate the association between environmental factors and ASD. MDPI 2023-09-13 /pmc/articles/PMC10532575/ /pubmed/37754843 http://dx.doi.org/10.3390/jox13030031 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Singh, Anisha Lawler, Cindy P. Walker, Vickie R. Pelch, Katherine E. Garton, Amanda E. Rooney, Andrew A. Haugen, Astrid C. Becoming aWARE: The Development of a Web-Based Tool for Autism Research and the Environment |
title | Becoming aWARE: The Development of a Web-Based Tool for Autism Research and the Environment |
title_full | Becoming aWARE: The Development of a Web-Based Tool for Autism Research and the Environment |
title_fullStr | Becoming aWARE: The Development of a Web-Based Tool for Autism Research and the Environment |
title_full_unstemmed | Becoming aWARE: The Development of a Web-Based Tool for Autism Research and the Environment |
title_short | Becoming aWARE: The Development of a Web-Based Tool for Autism Research and the Environment |
title_sort | becoming aware: the development of a web-based tool for autism research and the environment |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532575/ https://www.ncbi.nlm.nih.gov/pubmed/37754843 http://dx.doi.org/10.3390/jox13030031 |
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