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Infantile Hemangioma: A Cross-Sectional Observational Study

(1) Background: With an incidence of 4–10%, infantile hemangiomas (IH) are the most encountered benign tumors in infancy. Low birth weight (LBW), prematurity, female sex, multiple gestations, and family history of IH are some of the statistically proven risk factors for developing IH. The aim of our...

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Autores principales: Sandru, Florica, Turenschi, Alina, Constantin, Andreea Teodora, Dinulescu, Alexandru, Radu, Andreea-Maria, Rosca, Ioana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532986/
https://www.ncbi.nlm.nih.gov/pubmed/37763272
http://dx.doi.org/10.3390/life13091868
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author Sandru, Florica
Turenschi, Alina
Constantin, Andreea Teodora
Dinulescu, Alexandru
Radu, Andreea-Maria
Rosca, Ioana
author_facet Sandru, Florica
Turenschi, Alina
Constantin, Andreea Teodora
Dinulescu, Alexandru
Radu, Andreea-Maria
Rosca, Ioana
author_sort Sandru, Florica
collection PubMed
description (1) Background: With an incidence of 4–10%, infantile hemangiomas (IH) are the most encountered benign tumors in infancy. Low birth weight (LBW), prematurity, female sex, multiple gestations, and family history of IH are some of the statistically proven risk factors for developing IH. The aim of our study was to evaluate the prevalence of IH in our clinic and its connection to maternal and perinatal factors. (2) Methods: We conducted a cross-sectional study, over three years (2020–2022), at the Clinical Hospital of Obstetrics and Gynecology, “Prof. Dr. P. Sârbu”, in Bucharest, Romania. (3) Results: During this period, 12,206 newborns were born and we identified 14 infants with infantile hemangioma. In our study, the prevalence of infantile hemangioma was 0.11%. The prevalence of IH in pregnancies obtained through in vitro fertilization was 1%, in twin pregnancies it was 2.27%, and in those with placenta previa, it was 4.16%. (4) Conclusions: Our findings provide a solid image of the prevalence of IH in our country and underline that the development of IH is strongly connected to maternal and perinatal variables, such as: preterm newborns, in vitro fertilization, high blood pressure, anemia, hypothyroidism, placenta previa, and twin pregnancy.
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spelling pubmed-105329862023-09-28 Infantile Hemangioma: A Cross-Sectional Observational Study Sandru, Florica Turenschi, Alina Constantin, Andreea Teodora Dinulescu, Alexandru Radu, Andreea-Maria Rosca, Ioana Life (Basel) Article (1) Background: With an incidence of 4–10%, infantile hemangiomas (IH) are the most encountered benign tumors in infancy. Low birth weight (LBW), prematurity, female sex, multiple gestations, and family history of IH are some of the statistically proven risk factors for developing IH. The aim of our study was to evaluate the prevalence of IH in our clinic and its connection to maternal and perinatal factors. (2) Methods: We conducted a cross-sectional study, over three years (2020–2022), at the Clinical Hospital of Obstetrics and Gynecology, “Prof. Dr. P. Sârbu”, in Bucharest, Romania. (3) Results: During this period, 12,206 newborns were born and we identified 14 infants with infantile hemangioma. In our study, the prevalence of infantile hemangioma was 0.11%. The prevalence of IH in pregnancies obtained through in vitro fertilization was 1%, in twin pregnancies it was 2.27%, and in those with placenta previa, it was 4.16%. (4) Conclusions: Our findings provide a solid image of the prevalence of IH in our country and underline that the development of IH is strongly connected to maternal and perinatal variables, such as: preterm newborns, in vitro fertilization, high blood pressure, anemia, hypothyroidism, placenta previa, and twin pregnancy. MDPI 2023-09-04 /pmc/articles/PMC10532986/ /pubmed/37763272 http://dx.doi.org/10.3390/life13091868 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sandru, Florica
Turenschi, Alina
Constantin, Andreea Teodora
Dinulescu, Alexandru
Radu, Andreea-Maria
Rosca, Ioana
Infantile Hemangioma: A Cross-Sectional Observational Study
title Infantile Hemangioma: A Cross-Sectional Observational Study
title_full Infantile Hemangioma: A Cross-Sectional Observational Study
title_fullStr Infantile Hemangioma: A Cross-Sectional Observational Study
title_full_unstemmed Infantile Hemangioma: A Cross-Sectional Observational Study
title_short Infantile Hemangioma: A Cross-Sectional Observational Study
title_sort infantile hemangioma: a cross-sectional observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532986/
https://www.ncbi.nlm.nih.gov/pubmed/37763272
http://dx.doi.org/10.3390/life13091868
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