Cargando…
Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study
Background: It is important to determine the influence of traditional risk factors on the development of type 2 diabetes mellitus (T2DM) in young adults. Goal of the research: To study the incidence of T2DM and factors that increase the risk of its occurrence during the observation of a cohort of yo...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533043/ https://www.ncbi.nlm.nih.gov/pubmed/37763170 http://dx.doi.org/10.3390/jpm13091403 |
_version_ | 1785112104334786560 |
---|---|
author | Garbuzova, Evgeniia V. Shcherbakova, Lilia V. Rymar, Oksana D. Khudiakova, Alyona D. Shramko, Victoria S. Ragino, Yulia I. |
author_facet | Garbuzova, Evgeniia V. Shcherbakova, Lilia V. Rymar, Oksana D. Khudiakova, Alyona D. Shramko, Victoria S. Ragino, Yulia I. |
author_sort | Garbuzova, Evgeniia V. |
collection | PubMed |
description | Background: It is important to determine the influence of traditional risk factors on the development of type 2 diabetes mellitus (T2DM) in young adults. Goal of the research: To study the incidence of T2DM and factors that increase the risk of its occurrence during the observation of a cohort of young adults. Materials and methods: 1341 people aged 25–44 were included in the study from 2013 to 2017, of whom 622 were men (46.4%). The examination included anamnesis, anthropometric data, and a blood test. Cases of developed T2DM were identified by comparing the Diabetes Mellitus Register, medical records of patients, and the database of examined individuals from 2019 to 2023. T2DM Results: In the examined population, 11 participants (0.82%) developed T2DM. The prevalence of T2DM was 0.96% in men and 0.69% in women. Patients with T2DM had a higher waist circumference, BMI, SBP, TG, and lower HDL than patients without T2DM, and were also less likely to have a higher education. The risk of developing T2DM increases 6.5 times at a BMI of ≥30 kg/m(2), and 5.2 times at a TG level of ≥1.7 mmol/L, regardless of other risk factors. In the absence of a higher education, the risk of developing T2DM is increased by 5.6 times. Conclusion: In young people, high triglyceride levels, obesity, and a low level of education are associated with the risk of developing type 2 diabetes, regardless of other factors. |
format | Online Article Text |
id | pubmed-10533043 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105330432023-09-28 Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study Garbuzova, Evgeniia V. Shcherbakova, Lilia V. Rymar, Oksana D. Khudiakova, Alyona D. Shramko, Victoria S. Ragino, Yulia I. J Pers Med Article Background: It is important to determine the influence of traditional risk factors on the development of type 2 diabetes mellitus (T2DM) in young adults. Goal of the research: To study the incidence of T2DM and factors that increase the risk of its occurrence during the observation of a cohort of young adults. Materials and methods: 1341 people aged 25–44 were included in the study from 2013 to 2017, of whom 622 were men (46.4%). The examination included anamnesis, anthropometric data, and a blood test. Cases of developed T2DM were identified by comparing the Diabetes Mellitus Register, medical records of patients, and the database of examined individuals from 2019 to 2023. T2DM Results: In the examined population, 11 participants (0.82%) developed T2DM. The prevalence of T2DM was 0.96% in men and 0.69% in women. Patients with T2DM had a higher waist circumference, BMI, SBP, TG, and lower HDL than patients without T2DM, and were also less likely to have a higher education. The risk of developing T2DM increases 6.5 times at a BMI of ≥30 kg/m(2), and 5.2 times at a TG level of ≥1.7 mmol/L, regardless of other risk factors. In the absence of a higher education, the risk of developing T2DM is increased by 5.6 times. Conclusion: In young people, high triglyceride levels, obesity, and a low level of education are associated with the risk of developing type 2 diabetes, regardless of other factors. MDPI 2023-09-19 /pmc/articles/PMC10533043/ /pubmed/37763170 http://dx.doi.org/10.3390/jpm13091403 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Garbuzova, Evgeniia V. Shcherbakova, Lilia V. Rymar, Oksana D. Khudiakova, Alyona D. Shramko, Victoria S. Ragino, Yulia I. Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study |
title | Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study |
title_full | Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study |
title_fullStr | Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study |
title_full_unstemmed | Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study |
title_short | Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study |
title_sort | triglycerides, obesity and education status are associated with the risk of developing type 2 diabetes in young adults, cohort study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533043/ https://www.ncbi.nlm.nih.gov/pubmed/37763170 http://dx.doi.org/10.3390/jpm13091403 |
work_keys_str_mv | AT garbuzovaevgeniiav triglyceridesobesityandeducationstatusareassociatedwiththeriskofdevelopingtype2diabetesinyoungadultscohortstudy AT shcherbakovaliliav triglyceridesobesityandeducationstatusareassociatedwiththeriskofdevelopingtype2diabetesinyoungadultscohortstudy AT rymaroksanad triglyceridesobesityandeducationstatusareassociatedwiththeriskofdevelopingtype2diabetesinyoungadultscohortstudy AT khudiakovaalyonad triglyceridesobesityandeducationstatusareassociatedwiththeriskofdevelopingtype2diabetesinyoungadultscohortstudy AT shramkovictorias triglyceridesobesityandeducationstatusareassociatedwiththeriskofdevelopingtype2diabetesinyoungadultscohortstudy AT raginoyuliai triglyceridesobesityandeducationstatusareassociatedwiththeriskofdevelopingtype2diabetesinyoungadultscohortstudy |