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Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders
Obesity, hypertension, insulin resistance, and dyslipidemia are all clusters of an entity called “Metabolic Syndrome”. The global trends of this syndrome’s incidence/prevalence continue to increase reciprocally, converting it into a massive epidemic problem in the medical community. Observing the ri...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533132/ https://www.ncbi.nlm.nih.gov/pubmed/37763092 http://dx.doi.org/10.3390/jpm13091323 |
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author | Zakynthinos, George E. Tsolaki, Vasiliki Oikonomou, Evangelos Vavouranakis, Manolis Siasos, Gerasimos Zakynthinos, Epaminondas |
author_facet | Zakynthinos, George E. Tsolaki, Vasiliki Oikonomou, Evangelos Vavouranakis, Manolis Siasos, Gerasimos Zakynthinos, Epaminondas |
author_sort | Zakynthinos, George E. |
collection | PubMed |
description | Obesity, hypertension, insulin resistance, and dyslipidemia are all clusters of an entity called “Metabolic Syndrome”. The global trends of this syndrome’s incidence/prevalence continue to increase reciprocally, converting it into a massive epidemic problem in the medical community. Observing the risk factors of atrial fibrillation, a medical condition that is also converted to a scourge, almost all parts of the metabolic syndrome are encountered. In addition, several studies demonstrated a robust correlation between metabolic syndrome and the occurrence of atrial fibrillation. For atrial fibrillation to develop, a combination of the appropriate substrate and a trigger point is necessary. The metabolic syndrome affects the left atrium in a multifactorial way, leading to atrial remodeling, thus providing both the substrate and provoking the trigger needed, which possibly plays a substantial role in the progression of atrial fibrillation. Due to the remodeling, treatment of atrial fibrillation may culminate in pernicious sequelae, such as repeated catheter ablation procedures. A holistic approach of the patient, with simultaneous treatment of both entities, is suggested in order to ensure better outcomes for the patients. |
format | Online Article Text |
id | pubmed-10533132 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105331322023-09-28 Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders Zakynthinos, George E. Tsolaki, Vasiliki Oikonomou, Evangelos Vavouranakis, Manolis Siasos, Gerasimos Zakynthinos, Epaminondas J Pers Med Review Obesity, hypertension, insulin resistance, and dyslipidemia are all clusters of an entity called “Metabolic Syndrome”. The global trends of this syndrome’s incidence/prevalence continue to increase reciprocally, converting it into a massive epidemic problem in the medical community. Observing the risk factors of atrial fibrillation, a medical condition that is also converted to a scourge, almost all parts of the metabolic syndrome are encountered. In addition, several studies demonstrated a robust correlation between metabolic syndrome and the occurrence of atrial fibrillation. For atrial fibrillation to develop, a combination of the appropriate substrate and a trigger point is necessary. The metabolic syndrome affects the left atrium in a multifactorial way, leading to atrial remodeling, thus providing both the substrate and provoking the trigger needed, which possibly plays a substantial role in the progression of atrial fibrillation. Due to the remodeling, treatment of atrial fibrillation may culminate in pernicious sequelae, such as repeated catheter ablation procedures. A holistic approach of the patient, with simultaneous treatment of both entities, is suggested in order to ensure better outcomes for the patients. MDPI 2023-08-28 /pmc/articles/PMC10533132/ /pubmed/37763092 http://dx.doi.org/10.3390/jpm13091323 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zakynthinos, George E. Tsolaki, Vasiliki Oikonomou, Evangelos Vavouranakis, Manolis Siasos, Gerasimos Zakynthinos, Epaminondas Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders |
title | Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders |
title_full | Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders |
title_fullStr | Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders |
title_full_unstemmed | Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders |
title_short | Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders |
title_sort | metabolic syndrome and atrial fibrillation: different entities or combined disorders |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533132/ https://www.ncbi.nlm.nih.gov/pubmed/37763092 http://dx.doi.org/10.3390/jpm13091323 |
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