Head-to-Head Comparison of FDG and Radiolabeled FAPI PET: A Systematic Review of the Literature

FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging, which have demonstrated several advantages over [(18)F]FDG, especially in the case of low-grade or well-differentiated tumors. We conducted this systematic review to evaluate all the studies where a head-to-he...

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Detalles Bibliográficos
Autores principales: Guglielmo, Priscilla, Alongi, Pierpaolo, Baratto, Lucia, Abenavoli, Elisabetta, Buschiazzo, Ambra, Celesti, Greta, Conte, Miriam, Filice, Rossella, Gorica, Joana, Jonghi-Lavarini, Lorenzo, Lanzafame, Helena, Laudicella, Riccardo, Librando, Maria, Linguanti, Flavia, Mattana, Francesco, Miceli, Alberto, Olivari, Laura, Piscopo, Leandra, Romagnolo, Cinzia, Santo, Giulia, Vento, Antonio, Volpe, Fabio, Evangelista, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533171/
https://www.ncbi.nlm.nih.gov/pubmed/37763225
http://dx.doi.org/10.3390/life13091821
Descripción
Sumario:FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging, which have demonstrated several advantages over [(18)F]FDG, especially in the case of low-grade or well-differentiated tumors. We conducted this systematic review to evaluate all the studies where a head-to-head comparison had been performed to explore the potential utility of FAPI tracers in clinical practice. FAPI-based radiopharmaceuticals have shown promising results globally, in particular in detecting peritoneal carcinomatosis, but studies with wider populations are needed to better understand all the advantages of these new radiopharmaceuticals.

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