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Durable Anti-Vi IgG and IgA Antibody Responses in 15-Month-Old Children Vaccinated With Typhoid Conjugate Vaccine in Burkina Faso

We assessed anti-Vi IgG/IgA responses to typhoid conjugate vaccine (TCV) in children enrolled in a double-blind randomized controlled, phase 2 trial in Burkina Faso. Anti-Vi IgG seroconversion and anti-Vi IgA titers were higher in TCV than control recipients at 30–35 months post-vaccination. TCV ind...

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Autores principales: Ouedraogo, Alphonse, Diarra, Amidou, Nébié, Issa, Barry, Nouhoun, Kabore, Jean Moise, Tiono, Alfred B, Datta, Shrimati, Liang, Yuanyuan, Mayo, Ifayet, Oshinsky, Jennifer J, Tracy, J Kathleen, Girmay, Tsion, Pasetti, Marcela F, Jamka, Leslie P, Neuzil, Kathleen M, Sirima, Sodiomon B, Laurens, Matthew B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533206/
https://www.ncbi.nlm.nih.gov/pubmed/37589596
http://dx.doi.org/10.1093/jpids/piad058
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author Ouedraogo, Alphonse
Diarra, Amidou
Nébié, Issa
Barry, Nouhoun
Kabore, Jean Moise
Tiono, Alfred B
Datta, Shrimati
Liang, Yuanyuan
Mayo, Ifayet
Oshinsky, Jennifer J
Tracy, J Kathleen
Girmay, Tsion
Pasetti, Marcela F
Jamka, Leslie P
Neuzil, Kathleen M
Sirima, Sodiomon B
Laurens, Matthew B
author_facet Ouedraogo, Alphonse
Diarra, Amidou
Nébié, Issa
Barry, Nouhoun
Kabore, Jean Moise
Tiono, Alfred B
Datta, Shrimati
Liang, Yuanyuan
Mayo, Ifayet
Oshinsky, Jennifer J
Tracy, J Kathleen
Girmay, Tsion
Pasetti, Marcela F
Jamka, Leslie P
Neuzil, Kathleen M
Sirima, Sodiomon B
Laurens, Matthew B
author_sort Ouedraogo, Alphonse
collection PubMed
description We assessed anti-Vi IgG/IgA responses to typhoid conjugate vaccine (TCV) in children enrolled in a double-blind randomized controlled, phase 2 trial in Burkina Faso. Anti-Vi IgG seroconversion and anti-Vi IgA titers were higher in TCV than control recipients at 30–35 months post-vaccination. TCV induces durable immunity in Burkinabe children vaccinated at 15 months.
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spelling pubmed-105332062023-09-28 Durable Anti-Vi IgG and IgA Antibody Responses in 15-Month-Old Children Vaccinated With Typhoid Conjugate Vaccine in Burkina Faso Ouedraogo, Alphonse Diarra, Amidou Nébié, Issa Barry, Nouhoun Kabore, Jean Moise Tiono, Alfred B Datta, Shrimati Liang, Yuanyuan Mayo, Ifayet Oshinsky, Jennifer J Tracy, J Kathleen Girmay, Tsion Pasetti, Marcela F Jamka, Leslie P Neuzil, Kathleen M Sirima, Sodiomon B Laurens, Matthew B J Pediatric Infect Dis Soc Brief Reports We assessed anti-Vi IgG/IgA responses to typhoid conjugate vaccine (TCV) in children enrolled in a double-blind randomized controlled, phase 2 trial in Burkina Faso. Anti-Vi IgG seroconversion and anti-Vi IgA titers were higher in TCV than control recipients at 30–35 months post-vaccination. TCV induces durable immunity in Burkinabe children vaccinated at 15 months. Oxford University Press 2023-08-17 /pmc/articles/PMC10533206/ /pubmed/37589596 http://dx.doi.org/10.1093/jpids/piad058 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Ouedraogo, Alphonse
Diarra, Amidou
Nébié, Issa
Barry, Nouhoun
Kabore, Jean Moise
Tiono, Alfred B
Datta, Shrimati
Liang, Yuanyuan
Mayo, Ifayet
Oshinsky, Jennifer J
Tracy, J Kathleen
Girmay, Tsion
Pasetti, Marcela F
Jamka, Leslie P
Neuzil, Kathleen M
Sirima, Sodiomon B
Laurens, Matthew B
Durable Anti-Vi IgG and IgA Antibody Responses in 15-Month-Old Children Vaccinated With Typhoid Conjugate Vaccine in Burkina Faso
title Durable Anti-Vi IgG and IgA Antibody Responses in 15-Month-Old Children Vaccinated With Typhoid Conjugate Vaccine in Burkina Faso
title_full Durable Anti-Vi IgG and IgA Antibody Responses in 15-Month-Old Children Vaccinated With Typhoid Conjugate Vaccine in Burkina Faso
title_fullStr Durable Anti-Vi IgG and IgA Antibody Responses in 15-Month-Old Children Vaccinated With Typhoid Conjugate Vaccine in Burkina Faso
title_full_unstemmed Durable Anti-Vi IgG and IgA Antibody Responses in 15-Month-Old Children Vaccinated With Typhoid Conjugate Vaccine in Burkina Faso
title_short Durable Anti-Vi IgG and IgA Antibody Responses in 15-Month-Old Children Vaccinated With Typhoid Conjugate Vaccine in Burkina Faso
title_sort durable anti-vi igg and iga antibody responses in 15-month-old children vaccinated with typhoid conjugate vaccine in burkina faso
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533206/
https://www.ncbi.nlm.nih.gov/pubmed/37589596
http://dx.doi.org/10.1093/jpids/piad058
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