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Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts

BACKGROUND: Long-term extensive use of glucocorticoids will lead to hormonal necrosis of the femoral head, and osteoblasts play an important role in the prevention of osteonecrosis. However, there is no complete cure for necrosis of the femoral head. Mesenchymal stem cell- (MSCs-) derived exosomes a...

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Detalles Bibliográficos
Autores principales: Lu, Hongxu, Zhang, Zhaoxia, Wang, Zhaoying, Wang, Jinkui, Mi, Tao, Jin, Liming, Wu, Xin, Luo, Junyi, Liu, Yimeng, Liu, Junhong, Cai, Wenquan, Guo, Peng, He, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533242/
https://www.ncbi.nlm.nih.gov/pubmed/37771550
http://dx.doi.org/10.1155/2023/5537610