The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils

The maturation of liquid-like protein condensates into amyloid fibrils has been associated with several neurodegenerative diseases. However, the molecular mechanisms underlying this liquid-to-solid transition have remained largely unclear. Here we analyse the amyloid formation mediated by condensati...

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Detalles Bibliográficos
Autores principales: Linsenmeier, Miriam, Faltova, Lenka, Morelli, Chiara, Capasso Palmiero, Umberto, Seiffert, Charlotte, Küffner, Andreas M., Pinotsi, Dorothea, Zhou, Jiangtao, Mezzenga, Raffaele, Arosio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533390/
https://www.ncbi.nlm.nih.gov/pubmed/37749234
http://dx.doi.org/10.1038/s41557-023-01289-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533390/
https://www.ncbi.nlm.nih.gov/pubmed/37749234
http://dx.doi.org/10.1038/s41557-023-01289-9

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